DEFINITIONS
Aferesis is the separation of blood components directly to the person using the blood component separator
PURPOSE
Removing some blood components, can be either cell (cytopheresis) or plasma (plasmapheresis / plasma exchange)
Aferesis is the separation of blood components directly to the person using the blood component separator
PURPOSE
Removing some blood components, can be either cell (cytopheresis) or plasma (plasmapheresis / plasma exchange)
INDICATIONS
therapeutic:
• Sitoferesis
• Eritrositoperesis: Sickle cell anemia, malaria parasitaemia
• Tromboferesis: Trombositemia symptomatic
• Leukoferesis: Leukemia with hiperleukositosis, rheumatoid arthritis (in certain circumstances)
• Plasmapheresis: Abnormalities of paraprotein (hyperviscosity syndrome, cryoglobulinemia, Fabry disease, familial hypercholesterolemia), immunological abnormalities (Goodpasture's syndrome, myasthenia gravis, eaton-lambert syndrome, guailain-barre syndrome, pemphigus, ITP, an inhibitor of coagulation factor), vasculitis (SLE, glomerulonefriitis mesangiokapiler, Wagener's granulomatosis), deficiency of plasma factor (TTP), toxicity of drugs or other toxic materials.
donor:
To meet the needs of the patient's blood components:
• Tromboferesis
• Plasmapheresis
• Leukoferesis, to support the program PBSCT
therapeutic:
• Sitoferesis
• Eritrositoperesis: Sickle cell anemia, malaria parasitaemia
• Tromboferesis: Trombositemia symptomatic
• Leukoferesis: Leukemia with hiperleukositosis, rheumatoid arthritis (in certain circumstances)
• Plasmapheresis: Abnormalities of paraprotein (hyperviscosity syndrome, cryoglobulinemia, Fabry disease, familial hypercholesterolemia), immunological abnormalities (Goodpasture's syndrome, myasthenia gravis, eaton-lambert syndrome, guailain-barre syndrome, pemphigus, ITP, an inhibitor of coagulation factor), vasculitis (SLE, glomerulonefriitis mesangiokapiler, Wagener's granulomatosis), deficiency of plasma factor (TTP), toxicity of drugs or other toxic materials.
donor:
To meet the needs of the patient's blood components:
• Tromboferesis
• Plasmapheresis
• Leukoferesis, to support the program PBSCT
CONTRAINDICATIONS
• Aferesis therapeutic
• Patients with poor conditions and hemodynamic disturbances
• Aferesis donor
• Levels of platelet / leukocyte / albumin / hemoglobin / hematocrit below the normal
• ABO-Rh type is not suitable, cross matching the (+)
• Contain HBsAg / anti-HCV / HIV / VDRL and malaria
• less weight, old age, children
• Suffering from heart disease, lung, kidney failure, chronic or acute diseases other
• Aferesis therapeutic
• Patients with poor conditions and hemodynamic disturbances
• Aferesis donor
• Levels of platelet / leukocyte / albumin / hemoglobin / hematocrit below the normal
• ABO-Rh type is not suitable, cross matching the (+)
• Contain HBsAg / anti-HCV / HIV / VDRL and malaria
• less weight, old age, children
• Suffering from heart disease, lung, kidney failure, chronic or acute diseases other
PREPARATION
Materials and tools:
• Machine aferesis
• Set aferesis disposable, set trombaferesis, plasmapheresis sets, set leukaferesis, set eritositaferesis
• anticoagulant ACD-A
• Intravenous Access
• AV fisual
• Heparin injection of 0.9% saline infusion
• Albumin (to plasmapheresis)
• Emergency Drugs: Ca gluconate injection, inj adrenaline, corticosteroid inj, inj antihistamines, saline infusion, plasma expander, oxygen, resuscitation equipment and emergency drugs for resuscitation
Materials and tools:
• Machine aferesis
• Set aferesis disposable, set trombaferesis, plasmapheresis sets, set leukaferesis, set eritositaferesis
• anticoagulant ACD-A
• Intravenous Access
• AV fisual
• Heparin injection of 0.9% saline infusion
• Albumin (to plasmapheresis)
• Emergency Drugs: Ca gluconate injection, inj adrenaline, corticosteroid inj, inj antihistamines, saline infusion, plasma expander, oxygen, resuscitation equipment and emergency drugs for resuscitation
patients:
• Explanation of procedures that will be undertaken
• Physical examination: hemodynamics, weight, height
• Laboratory: ABO-Rh blood goals, cross-matching, DPL, HBsAg, anti HCV
• Informed consent
• Swallowing calcium tablets a day earlier
• Explanation of procedures that will be undertaken
• Physical examination: hemodynamics, weight, height
• Laboratory: ABO-Rh blood goals, cross-matching, DPL, HBsAg, anti HCV
• Informed consent
• Swallowing calcium tablets a day earlier
COMPLICATIONS
Hypocalcaemia (tingling lips and fingers, chest distress, dark view) hemodynamic disturbances and impairment of consciousness
Hypocalcaemia (tingling lips and fingers, chest distress, dark view) hemodynamic disturbances and impairment of consciousness
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